For UI based manual reversing of things that run on an OS, IDA is quite superior; it has really good pattern matching and is optimized on this use case, so combined with the more ergonomic UI, it’s way way faster than Ghidra and is well worth the money (provided you are making money off of RE). The IDA debugger is also very fast and easy to use compared to Ghidra’s provided your target works (again, anything that runs on an OS is probably golden here).

For embedded IDA is very ergonomic still, but since it’s not abstract in the way Ghidra is, the decompiler only works on select platforms.

Ghidra’s architecture lends itself to really powerful automation tricks since you can basically step through the program from your plugin without having an actual debug target, no matter the architecture. With the rise of LLMs, this is a big edge for Ghidra as it’s more flexible and easier to hook into to build tools.

The overall Ghidra plugin programming story has been catching up; it’s always been more modular than IDA but in the past it was too Java oriented to be fun for most people, but the Python bindings are a lot better now. IDA scripting has been quite good for a long time so there’s a good corpus of plugins out there too.