| ▲ | abainbridge 3 hours ago | |||||||||||||||||||||||||||||||||||||
Yep, I think it is. The point is there's almost no history of oral peptides, other than stomachs destroying them. FTA: "So to summarize the state of the art in oral peptide delivery: there are exactly two FDA-approved products that use permeation enhancers to get peptides into your bloodstream through your GI tract. Both achieve sub-1% bioavailability. Both required over a decade of development, thousands of clinical trial participants, and hundreds of millions of dollars." | ||||||||||||||||||||||||||||||||||||||
| ▲ | pstuart 2 hours ago | parent [-] | |||||||||||||||||||||||||||||||||||||
Would a sublingual dose be possible/more effective? Research in other (um, yeah, medicinal!) compounds shows that it can be an effective pathway to the bloodstream rather than trying to survive the digestive system. | ||||||||||||||||||||||||||||||||||||||
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