I have been doing the same commute at the same time for the better part of a decade. At this point I can look at my watch and tell if I'm ahead of schedule or behind schedule and infer what the compounding effect will be later in my commute.

I can easily shave 10% off my commute by lane changing to avoid the lanes where turn lane traffic tends to back up into the travel lanes, ramp traffic and "problem people". I test the null hypothesis several times a month by carrying bulky topheavy cargo that precludes a bunch of lane changing without more effort than I want to put in.

I don't think there's much to be gained by simply lane changing to chase fleeting gaps in traffic. The wins and losses will probably mostly cancel out.