"The Left Hand of Darkness" was published in 1969. I'm a transgender person in my 30s and Le Guin's writing makes me emotional every time I reread it. The ideas about gender and sexuality are more mainstream than they were almost 60 years ago, but the future is not evenly distributed and I think TLHOD would be eye opening for a lot of readers. Le Guin's prose and world building also place her among the best science fiction writers of all time.