I love Tilt.

With a single Tilt file combined with a docker compose file, almost all of the infrastructure you need is configured on a local machine. It also supports running kubernetes (most of the docs are around this), but you do not necessarily need to it it.My goto when I have more then 2 docker containers/services I want to keep changing code for. Some teams I work with usually have 20 such containers for local dev.

And yes, you can even nest Tilt files and even write normal python if you want to mix things up.