I think the important part here is "from scratch". Typically when you're designing a new (second, third, whatever) system to replace the old one you actually take the good and the bad parts of the previous design into account, so it's no longer from scratch. That's what allows it to succeed (at least in my experience it usually did).

These days software has been done a lot. You should be able to find others who have done similar things and learn lessons from them. Considering microservices - there are lots of people who have done them and can tell you what worked well and what didn't. Considering using QT - lots of others have and can give you ideas. Considering writing your own framework - there are lots of others: look at what they do good and bad.

If you are doing a CRUD web app for a local small business - there are thousands of examples. If you are writing control software for a space station - you may not have access to code from NASA/Russia/China but you can at least look at generic software that does the things you need and learn some lessons.