(author here) it's actually the module system of OCaml that's amazing for large-scale code, not the effects. I just find that after a certain scale, being able to manipulate module signatures independently makes refactoring of large projects a breeze.

Meanwhile, in Python, I just haven't figured out how to effectively do the same (even with uv ruff and other affordances) without writing a ton of tests. I'm sure it's possible, but OCaml's spoilt me enough that I don't want to have to learn it any more :-)