> What do you mean by 'any evidence that works better Than alternatives'?

I mean exactly that, clinical trials demonstrating that proton therapy is superior to radiation therapy. This is not a question about the physics but about how patients respond (and whether the expense of delivering proton therapy outweighs the expected marginal benefits).

As a non expert, I can't pronounce myself on the subject, I found this recent study:

https://www.mdanderson.org/newsroom/research-newsroom/proton...

But on the subject of discoveries and practical uses, the IBA cyclotrons are also used for other purposes than proton therapy: cleaning exotic fruits from dangerous substances and personalized medicine.