| ▲ | Two days of oatmeal reduce cholesterol level(uni-bonn.de) |
| 50 points by brandonb 3 hours ago | 41 comments |
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| ▲ | wwwtyro 18 minutes ago | parent | next [-] |
| My understanding is that: 1. When someone consumes fat, bile is released into the gut. 2. Oatmeal (and other soluble fibers like psyllium husk) capture this bile and it is excreted in stool. 3. In order to create the bile, the liver needs LDL. Because the LDL it used to create the bile was lost when it was captured, it exposes more LDL receptors and pulls LDL out of the bloodstream, thereby lowering LDL levels. It seems to me that in order to maximize the effectiveness of this LDL-lowering approach, one must not simply consume psyllium or oatmeal, but rather consume them in conjunction with fat. Not saturated fat, obviously, which raises LDL, but perhaps unsaturated or polyunsaturated fats. My expectation is that this would trigger the bile secretion required in order to actually sequester it. |
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| ▲ | mikestorrent 4 minutes ago | parent [-] | | So, me putting butter on my oatmeal is not gross and decadent, but actually the new health food craze? | | |
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| ▲ | wgjordan 17 minutes ago | parent | prev | next [-] |
| It's well known that an oatmeal diet lowers cholesterol (the article itself cites a 1907 'oat cure' in its intro). The new finding here is insight into the exact mechanism- a short-term, high-dose oatmeal diet (300g/day for two days) had significantly greater LDL-lowering effect than a medium-term, moderate-dose oatmeal diet (80g/day for six weeks), and they associated the difference with increases in several plasma phenolic compounds triggered by specific changes in the gut microbiome. |
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| ▲ | blinded 9 minutes ago | parent | prev | next [-] |
| Been trying to get into overnight oats (home made) for breakfast but its been hard to hit protein numbers, even with protein powder. |
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| ▲ | mikestorrent 5 minutes ago | parent [-] | | The study is suggesting two days of intense oats. You can go totally without protein for two days and barely notice it as long as you're keeping yourself full, and a big pile of oats does a surprisingly good job of that. |
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| ▲ | pogue an hour ago | parent | prev | next [-] |
| Working link
https://web.archive.org/web/20260124061041/https://www.uni-b... |
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| ▲ | carbocation an hour ago | parent | prev | next [-] |
| 300 grams of oatmeal a day, basically nothing else, and your LDL only goes down 10%. |
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| ▲ | brandonb an hour ago | parent | next [-] | | Definitely shows the comparative power of medications. Statins, ezetimibe, and PCSK9 inhibitors can reduce LDL or ApoB by 85-95%. | | |
| ▲ | smt88 an hour ago | parent [-] | | > Statins, ezetimibe, and PCSK9 inhibitors can reduce LDL or ApoB by 85-95% What? Absolutely not. Not even close. Provide a source if you really believe this. | | |
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| ▲ | lithocarpus 25 minutes ago | parent | prev | next [-] | | It seems as if some researchers think that reducing this single metric without considering any other factors is inherently always a good thing and is very important. | |
| ▲ | Snoozus 34 minutes ago | parent | prev | next [-] | | the diet was just maintained for two days | |
| ▲ | deadbabe 44 minutes ago | parent | prev [-] | | Hardly “nothing else”. Two smoothies a day with 150g of oats blended in them will basically cover this. You’d still have plenty of room for other food. | | |
| ▲ | addaon 42 minutes ago | parent [-] | | But that's not what the study tested. The study showed that both calorie restriction, and calorie restriction combined with almost all calories from oats, reduced cholesterol; but that the effect was more durable for the latter case. No data was gathered on eating oats without calorie restriction in this study. | | |
| ▲ | awesome_dude 29 minutes ago | parent [-] | | It seems more complicated than that - the "Oats only" people were only on that regime for two days, not an extended period of time. Also the paper says that the "Oats only" people were allowed to eat other fruits and vegetables with their meals. |
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| ▲ | wewewedxfgdf 31 minutes ago | parent | prev | next [-] |
| Oatmeal is food of the gods - BUT only if you don't pollute is with all sorts of add ons. Oatmeal and milk, nothing more. No fruit no nuts no sugar no honey no sprinkles of whatever. Perfect. |
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| ▲ | wisemang 22 minutes ago | parent | next [-] | | Bah. I love putting a layer of frozen blueberries at the bottom of the bowl then layering on piping hot steel cut oats to thaw and warm them up. You’re probably right that I shouldn’t add dried cranberries and a tiny drizzle of maple syrup on top (occasionally with thinly sliced bananas) but I’m happy enough to be wrong about it. I also skip the milk. | | |
| ▲ | mikestorrent 3 minutes ago | parent [-] | | You're missing out on up to two or three extra months of life by enjoying yourself now! I hope you think about that when you're too old to think about things! |
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| ▲ | postalrat 26 minutes ago | parent | prev | next [-] | | If you are taking out the sugar you might as well go all the way and take out the milk. | | |
| ▲ | pinkmuffinere 24 minutes ago | parent [-] | | It’s so funny you’re being downvoted, i think it’s just an expression of how much people hate oatmeal and like milk, lol. And also you can pry my milk from my cold dead hands. |
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| ▲ | antonvs 13 minutes ago | parent | prev | next [-] | | Milk? Why the exception for that? | | | |
| ▲ | deadbabe 22 minutes ago | parent | prev | next [-] | | Oatmeal and water | |
| ▲ | oguz-ismail2 26 minutes ago | parent | prev [-] | | *horses |
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| ▲ | doctorpangloss 44 minutes ago | parent | prev | next [-] |
| In hindsight, I would destroy the entire discipline of nutrition if it meant that literally every educated American woman growing up in the 70s (i.e., the non-immigrant grandmas) would no longer have an eating disorder or eating fixation related to weight loss. It would really improve the quality of the lives of many grandmas that are close and dear to me. Oatmeal is great, but truly, 70 year olds having more energy and being less weird is better. |
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| ▲ | renewiltord 43 minutes ago | parent | prev | next [-] |
| That’s nothing. You should have seen me on my Halo Top ice cream only diet. One point of the ice cream, nothing else. Lost way more weight than these losers. Halo Top, guys, it’s the key. |
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| ▲ | ProAm an hour ago | parent | prev | next [-] |
| This isn't news it's be known for decades? |
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| ▲ | roxolotl an hour ago | parent [-] | | Yea it’s on the oatmeal boxes even. Part of what’s interesting about this study though is they claim this two day intensive(300g per day) oatmeal diet showed microbiome changes which persist for months. | | |
| ▲ | throwaway173738 16 minutes ago | parent | next [-] | | Yeah for reference 54 grams is about 200 kcal, so this is 1200 kcal or so of just oats. That leaves 600-800 kcal for other food if you’re targeting 1800-2000 kcal/day which is a reasonable calorie restriction. So this isn’t really a sustainable diet in the long term. | |
| ▲ | zdw 44 minutes ago | parent | prev | next [-] | | 300g of oatmeal is about 3.3 cups (US measure). I would consider a normal bowl of oatmeal for breakfast to be about half a cup, so this is quite a bit more. | | |
| ▲ | ksherlock 30 minutes ago | parent [-] | | Yeah... a large (1" tall) canister of oatmeal is 1.2kg so imagine eating 2 big ass cans of oatmeal a week. | | |
| ▲ | brandon272 11 minutes ago | parent [-] | | I think you are mixing up oats and oatmeal. And I think (but am not positive) that the study is referring to 300g of prepared oatmeal. |
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| ▲ | fellowniusmonk 33 minutes ago | parent | prev [-] | | Oatmeal is fine, but has nothing on hulled barley. Oats are for horses. Mankind basically co-evolved with Barley. | | |
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| ▲ | sublinear an hour ago | parent | prev [-] |
| I think the main thing is to understand why oatmeal works: soluble fiber and the gut bacteria feeding on the carbs. That can be achieved within many other diets too. I wish they were more specific in saying what's special about oats, if anything. I also get upset when I see a ton of junk options at the grocery store. They are talking about plain cut oats and whole fresh fruit, but based on the way shelves are stocked I imagine a majority of people get the kind with all the added sugar. You might as well be eating honey smacks at that point. Yogurt has the same problem at the store. |
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| ▲ | bhk 25 minutes ago | parent [-] | | Hold on there. High fiber consumption increases the excretion of cholesterol, by reducing the reabsorption of the cholesterol in bile. The liver produces cholesterol for bile, which mixes with our food in the duodenum and aids absorption of fats. Most of this cholesterol is then re-absorbed by the small intestines. By increasing bulk, fiber reduces the amount that is re-absorbed. Effects on but biome are real too, and apparently beneficial, and may factor in, but it isn't the only (or necessarily the primary) mechanism for reducing serum cholesterol. |
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