One needs to go a fair ways off the beaten path before they'll start running into trouble like that under macOS and Windows.

For macOS in particular, most trouble that more tinker-y users might encounter disappears if guardrails (immutable system image, etc) are disabled. Virtualization generally "just works" by way of the stock Virtualization.framework and Hypervisor.framework, which virtualization apps like QEMU can then use, but bespoke virtualization like that QEMU also ships with or that built into VirtualBox and VMWare works fine too. No toggles or terminal commands necessary. Linux does get virtualized a lot, but people frequently virtualize Windows and macOS as well.