Please don't lazily conclude that he's gone crazy because it doesn't align with your prior beliefs. His work on Covid was just as rigorous as anything else he's done, but it's been unfairly villainized by the political left in the USA. If you disagree with his conclusions on a topic, you'd do well to have better reasoning than "the experts said the opposite".

Ioannidis' work during Covid raised him in my esteem. It's rare to see someone in academics who is willing to set their own reputation on fire in search of truth.