Homer is a great example for this. However, at the end of the day, through all his incompetence and bumbling, he wins. He has a wonderful wife, kids and a home. He has friends and always has an upbeat “winner” attitude. You see him and see a happy, successful person inspite of his failings.

Same with Peter Griffin but he is confident and fiercely dominant. He doesn’t feel like a loser.

Even Michael from the office who is a “loser”, has a lot of redeeming qualities like genuine care for his employees, terrific salesman and a position of leadership.

Great point! Would the Simpsons have done as well had Homer just gotten screwed over and miserable? I would bet not. In the American culture that sort of reality would have shifted the humor into more of a "feels bad man" that probably wouldn't have gone over well.