As of yet, the AI models doing important work are still pretty specialized. I'd be happy to pitch in to run something like an open source version of alpha-fold, but I'm not aware of any such projects.

I have trouble seeing LLMs making meaningful progress on those frontiers without reaching ASI, but I'd be happy to be wrong.

I think part of the problem/difference is that all "important work" needs to be auditable and understood by humans. We need to be able to fix bugs, and not just roll the dice and hoping that a lack of symptoms means everything is cured.