100% I used to have a 43-inch 4K "monitor" (16:9). The lack of curvature meant that at the sides of the screen, there was noticeable color shifting due to variations in viewing angle. That's with an IPS panel.

Your dream is probably a ~50in 8K TV (with RGB pattern if you are on macOS), but curved. I don't know if that will ever exist.

Personally, I found that with a bigger 16:9, I would not use the top and bottom of the screen. When I "downgraded" to a 40in ultra-wide, there was not much difference in the space I was using.