AA Flight 191 in 1979, 273 dead. American Airlines invented their own engine removal procedure using a forklift and damaged a pylon and mounting bracket. The engine ripped off the wing on takeoff.

Interestingly, the reason American Airlines was removing the engines (and pylons) in the first place was to replace that same aft bearing. McDonnell-Douglas had found that the aft bearing could wear out sooner than expected and issued a service bulletin requiring replacement. There is mention of it in the AA191 NTSB report[1] and also at Admiral Cloudberg's article on the accident[2].

[1] https://www.ntsb.gov/investigations/AccidentReports/Reports/... [2] https://admiralcloudberg.medium.com/rain-of-fire-falling-the...