I didn't watch the video, but assuming they used a mass spectrometer, the end result will be identical to the real thing, anyone tasting otherwise is deluding themselves.

The video explains how the gas based mass spectrometers he had (indirect) access to don't normally pick up nonvolatile compounds like tannins. It was a big breakthrough that since he didn't have cocoa leaf extract, and he basically nailed everything else, he couldn't really understand what he was missing until he realised the extract would likely contain tannins.

So there may be other nonvolatile compounds which nevertheless impact the flavour profile. While a lot of flavour is in your nose, not all of it is...

This is wrong.

Same with perfume knock-offs

Spectrometer doesn’t tell you quantities, mixes, what have you.

You can emulate 90% of the first smell but never in life you can replicate entire bouquet, aftersmell, propriety molecules, etc.

He doesn't compare the mass spec of his final product to a real coke, unless I missed it.

Taste buds can detect chemicals in as concentrations as low as a few parts per million, I dunno.

Mass spec is indeed demonstrated multiple times