I am often frustrated by ads/sponsored content on YouTube that I cannot buy. Youtuber present me nice product targeted for US audience. I am in Europe. No way I can use it or buy it. I would do it sometimes, but I cannot. Still I have to watch such ads.

I dont think there is a practical way to prevent this case.

That's the funny part, ads would be less annoying if they were hyper-targeted, which means there was more supply of ads and worse privacy. There's been a number of times I've found useful stuff from ads, but it's rare and almost never on Youtube.

Youtube is the one site worth paying for not to see ads and sponsorblock extension skips the live reads.