I've maybe used Wayland on Gnome for 1-2 years at this point, always with nvidia hardware. Works OK now, but didn't 2 years ago, and before that, used to be very janky, today is smoother than Xorg. But at this point, I don't think there is a single blocker left for me. Took some time to rewrite some programs that I have to control their own window position and wants to see what other applications are running, but was easy to work around with a Gnome Shell Extension in the end, as the design of Wayland doesn't really "allow" those sort of things.

I'm having more issues with games/websites/programs that didn't take high display refresh rate into account, than Wayland, at this point.