On uBlock Origin settings > Filter lists > Annoyances

Check all the items [1] and it may improve your experience with modern pop-ups.

[1] https://imgur.com/a/2jkf6YA

Yup this works really well.

Only issue I've seen is that sometimes it blocks a poorly implemented cookie popup. This means it can't be handled by Consent-O-Matic either and then the site becomes unresponsive because it's waiting for a cookie choice.