While it is possible to use "semantic" styling and page layouts and templates in Word, I would argue that Word owes its popularity to the fact that no user is surprised when they select text, change the font, it does not change it anywhere else.

It is one of the tools that popularised "WYSIWYG" as an approach, and as we know from many other tools, you lose something when you adopt a tool like that.

Now, I'd always recommend and use a TeX-based document layout system (but despite my huge respect for DEK, not Computer Modern family of fonts, even for mathematics), but many struggle with non-visual document entry: it is no surprise scientific community is the only one which standardized on it since inputting mathematics visually is a PITA.