I feel like many people in the comments aren't aware that Karpathy is an ML scientist for whom programming is a complementary skill, not a profession. The only reason he came up with "vibe coding" is because maximum complexity of his hobby projects made it seem believable. Maybe take his opinions about fate of programming with a grain of salt.

He is brilliant no doubt, but not in that field.

Exactly, I would put more weight on this if it were coming from someone who actually works as a regular programmer in the industry

This is such a great way to frame all his comments.