I guess it would, but remember there are more services out there than just HTTP(S).

For example the last time I had an IPv6-only host I had issues cloning things from github, as "git clone git@github.com..." failed due to github.com not having IPv6 records.

A quick search revealed this open 3+ year old discussion - https://github.com/orgs/community/discussions/10539

You’re in luck, github is in the process of moving to azure!