For most any 5G network you should be safe to 1420 - 80 = 1340 bytes if using IPv6 transport or 1420 - 60 = 1360 bytes if using IPv4 transport.
For testing I recommend starting from 1280 as a "does this even work" baseline and then tweaking from there. I.e. 1280 either as the "outside" MTU if you only care about IPv4 or as the "inside" MTU if you want IPv6 to work through the tunnel. This leverages that IPv6 demands a 1280 byte MTU to work.