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imiric 10 hours ago

While that's true, I don't consider psychedelics to be within the same realm of safety as cannabis. Cannabis does have psychoactive effects, of course, but it doesn't induce visual and auditory hallucinations with the intensity that LSD, psilocybin, or even MDMA do. I do think that cannabis can make mental disorders such as anxiety worse in people who are already prone to them, but psychedelics are far more dangerous in that sense, especially with higher dosages. These effects can sometimes persist long after the effects of the substance wear off.

Also, synthetic compounds such as LSD and MDMA which have only been around for a ~century don't have the historical record of cannabis, psilocybin, and other substances found in nature, which humans have consumed for thousands of years. So to me those are intuitively less "safe".

chneu 8 hours ago | parent [-]

Dosage matters. Lots of folks take psilocybin and lsd on a daily basis.

Also the weed we smoke today is absolutely nothing like historical cannabis. The potency is hundreds of times higher, depending on what they're breeding for.

imiric 5 hours ago | parent [-]

> Dosage matters. Lots of folks take psilocybin and lsd on a daily basis.

Microdosing is not the same as recreational usage. Not many people take LSD or psilocybin recreationally that often. Cannabis recreational usage is much more common, with far lower health risks.

> Also the weed we smoke today is absolutely nothing like historical cannabis.

It's much stronger, but I wouldn't say it's "absolutely nothing" like historical cannabis. The way we consume it (concentrates, edibles, etc.) also makes it much more potent. But even that pales in comparison with the effects of moderate doses of psychedelics, which can have lasting psychological effects.

So, sure, dosage matters, but these substances have fundamentally different psychoactive effects.