> For example, it's pretty widely agreed that it (anecdotally) causes anxiety at higher doses - how high of a dose?

Not for everyone. My understanding is that some people are more susceptible to experiencing anxiety when consuming, while others won’t even at high doses. I personally have pretty high anxiety in general, vaping <10mg of cannabis is really relaxing and makes my anxiety completely go away.

The only kind of bad experience I had was when I first tried a dry herb vape, it was maybe 1h after taking my ADHD meds and the combination resulted in the craziest out of body experience I’ve ever had (it wasn’t too bad, but pretty overwhelming at the time)