I was a fairly heavy user of Perl, but eventually migrated to Python. The primary reason was the generally abysmal quality of what was in CPAN compared to what was available as third-party packages for Python. I found myself having to spend way too much time fixing stuff I pulled down from CPAN far more than I'd need to for Python for the same functionality. Undoubtedly Perl stuff got better, but I didn't have time to wait.

I mainly moved on to Python because the startup time for scripts seemed to be a lot worse for Perl. I was a heavy Perl user in the 90's and early 2000's.