I think the question is do you want to actually stop certain entities from using the project, or do you just want to send a message? If you want to actually stop them then ultimately there is only one way, which is you sue them. If you're not willing to aggressively sue people who use your software in ways you don't want, then I think there's little point in taking the time to craft a license that expresses acceptable uses.

If you just want to send a message, then you can change the license and not take any further action.