Recent experience report: I updated four of my team's five owned microservices to .net 10 over the past two weeks. All were previously on .net 8 or 9. The update was smooth: for the .net 9 services, I only had to update our base container images and the csproj target frameworks. For the .net 8 services, I also had to update the Mvc.Testing reference in their integration tests.

It's hard for me to imagine a version increment being much easier than this.

I'm currently migrating dozens of projects to .NET 10. All of them so far were basically one line changes and a recompile.

You should be able to go from .NET 6->10 without almost any changes at all.