This is probably unrelated, but I used to play a lot of DotA for years (at some points for 12 hours a day), then quit cold turkey, then started again last year, but maybe 30-60 minutes a day.

After I started Mounjaro, I haven't really had the urge to play at all. I played a game a few weeks ago but I was kind of "meh" about it, and haven't played since. It's striking.