> Every medication can have severe and permanent side effects

SSRIs are by an order of a magnitude worse than any other common medication in that respect.

Moreover, like I said there's little evidence these drugs actually achieve any quality-of-life improvement beyond a placebo effect.

SSRIs are very bad, but antipsychotics are worse. There are many other reasons, but a demonstrative one is that there is a cumulative annual risk as high as 7% of developing a permanent movement disorder when on them.