I think the game Cross Code (a game written in JS) was ported to consoles using a pretty complex process.

Here is a detailed blog post about the topic : https://www.radicalfishgames.com/?p=6892

Yeah, I saw the video about that earlier which is what led me to wonder if there was a native JS way now.

They used Kha in order to port only the console versions, the desktop versions remained JS from my understanding: https://github.com/Kode/Kha which is built on top of Haxe. This works, but it also means not having a single codebase anymore which would be one of the benefits of a JS based system.

There are other options here - something like using an AOT JS compiler like Porffor, but from my understanding it's never been tested (and would probably be missing a lot of support to get it working - like shimming canvas & providing a WebGPU context that the compiled JS could execute against).