I just wish my hands wouldn't cramp on hand-held devices. I've never been able to use handhelds for longer than thirty minutes.

Goes for console controllers too.

Apologies if you've already ruled this out, but hand pain is very often caused by strain/injury from further up the arms, the shoulders, or even the neck. You may find that pulling your shoulders back or relaxing them, or adjusting your arm posture, or straightening/relaxingyour neck gives you less pain while playing.

Maybe you need larger controllers ?

Also possible the touchpads are better for fatigue than joysticks