What is "detox inefficiency"?

EDIT - I ask because the only results I get when searching are a Harvard article debunking it. I'd rather hear the opinion of someone that actually believes in it before I read about why it's all malarky. I believe in arguing against the best version of someones argument.

https://www.health.harvard.edu/staying-healthy/the-dubious-p...

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DANmode 6 hours ago | parent [-]

https://my.clevelandclinic.org/health/body/glymphatic-system

PS Thanks for keeping this a good place to be!

https://news.ycombinator.com/newsguidelines.html

More for the avid reader:

1.) https://pmc.ncbi.nlm.nih.gov/articles/PMC7698404/

2.) https://pubmed.ncbi.nlm.nih.gov/40012567/

3.) https://pubmed.ncbi.nlm.nih.gov/36498538/

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purple_turtle 6 hours ago | parent [-]

Your first linked page has no word "depression" on it

	▲	DANmode 5 hours ago \| parent [-]
		It wasn’t intended to. It was just the best “every man” link I could provide for understanding how efficacy of toxin-clearing (toxicity) could be related to depression, other struggles with homeostasis. Did you grasp the connection?