I'm sure "major project" is a subjective label, but Flow made headlines earlier this year with an Academy Award (Best Animated Feature) and Golden Globe (Best Animated Feature Film)

https://flow.movie/

https://www.youtube.com/watch?v=ZgZccxuj2RY

https://www.blender.org/user-stories/making-flow-an-intervie...

Flow is good filmmaking expressed through low-tech production, which is totally valid, but it doing a lot with a little isn't going to stop Disney from one-upping themselves with the next Zootopia movie so Blender needs to handle that angle too if it's going to become a catch-all solution for all kinds of production.