Remix.run Logo
ajoseps 13 hours ago

i thought the first two have had huge improvements in the last decade?

trenchpilgrim 13 hours ago | parent | next [-]

HIV has become a manageable disease in my lifetime. The main issue today is access to medication as I understand it.

toomuchtodo 13 hours ago | parent [-]

The first widespread cure for HIV could be in children - https://news.ycombinator.com/item?id=44765981 - August 2025

One-and-done HIV protection in infants - https://news.ycombinator.com/item?id=44736988 - July 2025 (First author of the paper even commented here at the time: "labanimalster - First author here. We solved a 30-year problem in gene therapy by leveraging neonatal immune tolerance. A single AAV vector injection encoding HIV antibodies achieved 89% success in newborns vs 33% in 2-year-olds, with protection lasting through adolescence. This could transform HIV prevention in regions where maintaining regular medical care is challenging. Happy to answer questions about the science or implications.")

US FDA approves Gilead's twice-yearly injection [lenacapavir] for HIV prevention - https://news.ycombinator.com/item?id=44312729 - June 2025

agumonkey 13 hours ago | parent | prev | next [-]

it might be slow exponential thing, 60 years of low to medium improvements in cancer, and hopefully suddenly a few big cracks to turn it into a chronic liveable condition (or maybe cure it).

there are more articles about advanced tumors being shrunk to nothing than before (based on my personal monitoring)

ashleyn 13 hours ago | parent | prev [-]

HIV prevention has been reduced to a twice a year shot given mainly to MSM. It's pretty damn close to the original goal of a vaccine.