I checked it out and it looks good on paper but it only runs on Bun.

Don't get me wrong, I use Bun and I'm happy with it, but it's still young. With Hono/Drizzle/Zod I can always switch back to Node or Deno if necessary.

ElysiaJS's blog claims that support for other runtimes was added in 1.2: https://elysiajs.com/blog/elysia-12.html#adapter