I've been running Fedora at home for about a decade now, and I've been doing my gaming on it for the majority of that period.

I've been running Fedora at work for about 6-7 years now too, with few issues. Work binned Adobe XD and moved to Figma which has made it even more viable.

The one and only holdout I keep a Windows 11 install around for is VR. With Valve's new headset due to release any week now, we will hopefully have a bunch of Linux SteamVR patches on the way to sand the remaining sharp edges off.