It is probably down to whether you find humor in absurdity as the far side leans rather hard into this.

The humor "is" very weird, the normal flow is a strange image that is not funny and a simple caption that is also not funny. but coupled together there is something funny about the absurd connection that is made. sort of like a caption meme with better drawing. And honestly I think there are a lot of them that we just don't "get", too strange for comprehension, and we find this funny as well.

I can imagine Farside might be hard to "get" for someone meeting it in 2025 - absurdity to the extreme is everywhere now. You can think of it as Skibidi Toilet for a slower, more innocent time.