Some VPN applications provide the means by which to tunnel WG over TCP. Some provide those as standalone tools: <https://github.com/mullvad/udp-over-tcp>

The one above has a very simple protocol:

    The format of the data inside the TCP stream is very simple. Each datagram is preceded with a 16 bit unsigned integer in big endian byte order, specifying the length of the datagram.

If you are doing it manually you can include two peers, one over UDP and one over TCP and prioritize traffic flow over the UDP one. Commercial VPN apps tend to handle that with "auto".

If you want to be fancy or you are confident that the UDP blocking service can offer high performance you can include a third peer using udp2raw: <https://github.com/wangyu-/udp2raw>

The reason why you may want to retain udp-over-tcp is that some sophisticated firewalls may block fake-TCP.