I am using a LaTeX pipeline for creating text, invoices, forms, etc. from snippets stored in a database. It was quite complicated to set up, but the results are very satisfying. In principle, I would like an easier markup language, but am afraid to wast my time trying out something new, just to run into limitations after awhile.

Here are my most important requirements: Multiple columns configurable for meaningful column and page breaks (minimum number of lines in a new column or page). Reliable automatic hyphenation for multiple languages (at least English and German, perhaps French, Italian and Spanish in the future). Pictures in columns with dynamic placing according to the available space. Complex tables and forms with sensible automatic page breaks. Background images. Different areas on the page which are treated like mini-pages. -- Is Typst capable of all that?

Now, this isn't really an alternative, but I can recommend using pandoc instead of pure LaTex. Personally, I think text blocks are much easier to handle and read in markdown and pandoc allows you to use in-line LaTex wherever markdown is insufficient, without making basic text styling unnecessarily verbose. In my opinion, the result is a better/friendlier LaTex, or limitless markdown respectively. Especially for writing papers and such, you can always start actually writing in basic markdown, which is trivial and almost-WYSIWYG, and later worry about presentation. In my experience, with pure LaTex you easily get lost in sidequests and it's much harder to get into a writing flow and find your way around your own words in the editor.

I haven't done pictures in columns but the rest should be doable.

I've migrated my invoicing (and all my other publishing/slides) to typst from latex and couldn't be more happy.