Arguably/pedantically, Pyodide has had this for a while: see https://developer.nvidia.com/blog/sandboxing-agentic-ai-work... for a use case.

Wasmer's approach hints at faster cold starts and better overall performance; the benchmarking against pyodide is a bit unclear, and it's unclear to me whether that would make or break viability for a use case like this.

But one thing this does make possible is if your arbitrary script is actually a persistent server, you can deploy that to edge servers, and interact with your arbitrary scripts over the network in a safe and sandboxed way!

I hadn't seen that NVIDIA article before... turns out they're running Python inside Pyodide inside WebAssembly inside Chrome inside Playwright inside Node.js! https://github.com/JosephTLucas/wasm-plotly/blob/main/server...

I'm always on the lookout for ways to run Python in a sandbox but that feels like one too many levels for me.

Pyodide inside Deno removes at least the headless browser layer: https://til.simonwillison.net/deno/pyodide-sandbox