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brahyam 3 days ago

> This is also the basis for exercise - your muscles and tendons are damaged when you work out, but they get rebuilt stronger

This is an outdated view, evidence shows muscle/tendon growth/adaptation occurs primarily via mechanical tension and metabolic stress, with damage playing a minimal or even counterproductive role. hypertrophy happens despite it, not because of it.

[The development of skeletal muscle hypertrophy through resistance training: the role of muscle damage and muscle protein synthesis. Schoenfeld et al., 2017](https://pubmed.ncbi.nlm.nih.gov/29282529/)

pazimzadeh 3 days ago | parent [-]

That’s interesting, thanks for the link.

Nevertheless, exercise turns on repair pathways in multiple tissue types.

Molecular mechanisms of exercise contributing to tissue regeneration (2022) https://www.nature.com/articles/s41392-022-01233-2

Exercise Promotes Tissue Regeneration: Mechanisms Involved and Therapeutic Scope (2023) https://pmc.ncbi.nlm.nih.gov/articles/PMC10164224/