Yes, I'm exactly that situation. Mid-40s. My background is in finance - investment banking. I spent 16 years at the same firm, before being actively recruited over to an industry-leading bank but in an adjacent sector (UHNW lending). Less than a year into that, I was laid off as part of a large reduction in force. "Sorry, last in first out, here's two weeks". Thankfully the RIF was large enough that it triggered a WARN Notice, so I got an additional 3 months out of it.

I've gone through my network multiple times, asked for referrals, have applied to 2,000+ job openings that I've seen on LinkedIn, have tried networking meetings, you name it. I'm in NYC and not geographically mobile (raising 2 kids, divorced), but I've applied to jobs in FL, Chicago, etc where I would try to make it work being in an office part time around my schedule. I've applied to totally different sectors.

The recruiting merry-go-around is brutal. ATS to enter resume data, automatic rejection emails (sometimes within under 24h!). The "what have you done the last two years" question kills me -- I've looked for a job, that's what I've done.