I have a friend who has run it for charity multiple times. They're a six-ish-plus hour marathoner. My partner has run them in the last 10 miles a couple of times pre-bombing. Her take is that it's pretty miserable if you're that slow because they start breaking down the course, the aid stations get light on supplies, and the porta-potties get unspeakable. So yeah, you can, but it would be a better experience if you're not quite so far behind a BQ time.

As for me, I don't run. Props to anyone who can run a BQ and enjoy it.