I remember when there was option to run any application. With Sequoia there are only 2 options: App Store; App store + Known developers. Third option was removed. You can still run other apps but you need to manually approve them with ~3 popups where first option is "move to Bin". You need to do this after every OS or App update. I wonder when this option will be removed as well.

It's been missing since at least Big Sur, so if they're going to go any further they do seem to be taking their time over it.