Removing the wrapping newline from the FASTA/FASTQ convention also dramatically improves parsing perf when you don't have to do as much lookahead to find record ends.

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Gethsemane a day ago | parent | next [-]

Unfortunately, when you write a program that doesn't wrap output FASTAs, you have a bunch of people telling you off because SOME programs (cough bioperl cough) have hard limits on line length :)

	▲	sharedptr 11 hours ago \| parent \| next [-]
		Is BioPerl still standard, did people move to BioPython? When I was shown BioPerl I was tempted to write a better, C++ version, but was overwhelmed by other university stuff and let it go.
	▲	o11c a day ago \| parent \| prev [-]
		You can use content-defined chunking to wrap at a predictable place so that compression still works.

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bede a day ago | parent | prev [-]

Thanks for reminding me to benchmark this!

	▲	totalperspectiv a day ago \| parent [-]
		I've only tested this when writing my own parser where I could skip the record end checks, so idk if this improves perf on a existing parser. Excited to see what you find!