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amelius a day ago

And the compressor does not think: "how can I make these two sequences align better without wasting a lot of space?"

ebolyen a day ago | parent | next [-]

No, because alignment, in the general case, is O(n^2). It is ironically one of the more tractable and well solved problems in bioinformatics.

tiagod a day ago | parent | prev [-]

The compressor doesn't think about anything. Also, Zstd doesn't have the goal of reaching the highest possible compression ratio. It's more geared toward lowest overhead, high bandwidth compress/decompress.