For this to truly be funny, it needs to be installed on on an unsuspecting user’s laptop, preferably some C-level type about to join an in-person board meeting.

I don't have a C-level to hand. My daughter's university laptop, however is just here...

We had a classmate would would wander off with his laptop unlocked so one day we set all his system sounds to fart noises and cranked up the volume. He came back to class minimized a window and the whole class heard the noise and cracked up. We also got good mileage out of adding a wireless mouse on another occasion and zipping his cursor around the screen for probably a good ten minutes.