I spent 7 months on a contract job last year like that... I'm in Phoenix (as well as half the employees involved) but the meetings were East Coast centered, so starting at 5am local. Roughly 38 hours of meetings a week, and in a position where I had to pay attention... It SUCKED so hard... I never got used to being up early and it just burned me up.

At least with actual people, in person there's more to the communication... I miss lunch with coworkers. I now pretty much have to work from home (vision decline, so I cannot drive), I wish it weren't the case.