> It's thought that life on Earth started with RNA mayhem, not with vessels to isolate from it.

They're not mutually exclusive. You could have various kinds of autocatalytic sets of molecules, including RNA, inside and outside lipid vesicles, and some of them might have re-produced better than others. Anything that could have happened in an open ocean of nuleotides and amino acids could also take place within a lipid vesicle, just that within some vesicle maybe the right concentrations of molecules had at some point emerged that could more easily reproduce itself than in the open ocean where the particular autocatalytic set could be washed away by the surrounding molecular chaos.